Posted: 09 April 2007 at 3:34pm | IP Logged

Thought you may like a peek at this. PS is very flexible as you can see, chocolate spread, drinks and nutrition bars all seem to provide a great medium! I have posted the link for the clinical trials in Israel in the OP, this is what we  have found out since. It must have been phase 1 of the trials.

Must stress though that we see a HUGE difference with AD'H'D, the H being very important. ADD's do not seem to see the benefits nearly as much.

01.06]
Enzymotec launches a dietary solution to ADHD/ADD in kids

A recent clinical study conducted at the Tel-Aviv Sourasky Medical
Center, has demonstrated the great potential of a natural, safe and
effective alternative to those who are concerned from the psychiatric
stimulators commonly used for ADHD treatment.

  "In this double-blind, placebo-controlled trial, performed on 90 ADHD
children, we have shown that a daily consumption of a unique natural
lipid-based carrier, lead to a significant improvement of their
cognitive performance, as observed by the TOVA test scores" says Dr.
Dori Pelled, Director of Clinical Research at Enzymotec. "The fact that
this novel ingredient is based on decades of research in the field of
brain-lipids and their relation to cognition, leads us to high
confidence in these results" concludes Dr. Pelled.



Attention deficit and hyperactivity disorder (ADHD) is the most common
chronic disorder in children. It affects roughly 4-7% of the children
population, and is thought to accompany 50-60% of the children even
after maturation.  "Until today no one has been able to explain the
rapid emergence and growth of this indication" says Enzymotec CEO, Dr.
Ariel Katz.  The use of ADHD drugs (mainly Ritalin and Concerta) is
strongly criticized by parents who resent their sedative effect and
fear that it will have a negative impact on the child's self-image and
normal maturation. Additional concerns are their side-effects which are
mainly loss of appetite and troubled sleep.  "We are certain that the
market is ready for an effective, safe and science-based supplement.
Unfortunately, so far supplements such as iron or DHA have shown
marginal effect only. In our study we have used a chocolate spread for
delivering our ingredient to the kids, so we are confident that our
novel supplement can be delivered in a variety of user-friendly forms
appealing to kids such as syrups or chewable tablets" concludes Dr.Katz.



Enzymotec is an Israeli biotech company, developing bio-functional
nutraceuticals among which are: SharpPS for improving cognitive
performance in the elderly, InFat for balanced nutrition in infant
formulas and CardiaBeat for reducing CVD risks.

Posted: 12 April 2007 at 12:05pm | IP Logged

Hi There,

I think I am going to try this. I have a 6 year old on the AS with severe hyperactivity. I have tried GABA with no luck and right now I am giving him DMAE, Taurine and Cal/mag. It has helped a little bit but mostly with his sleep. It does not seem to help with the hyperactivity and impulsiveness during the day. I went to the vitacoast website and there are a bunch of them.  How do I know which one to get. I want the one that will work the best for him and since I have never used it I am not sure which one to use.  Thanks.

Teri

Posted: 12 April 2007 at 2:35pm | IP Logged

Hi,

My son has ADHD-Inattentive type tendencies and I did not find any noticeable improvement in him with PS. Maybe PS works only for ADHD  hyperactive types. Some websites do say that it helps with attention, though.  I tried the same PS that Sparkli recommended which has 100 mg PS. May be the dosage was not enough ? I do not know. Good luck to you all.

Thanks,MM

Posted: 12 April 2007 at 3:10pm | IP Logged

MightyMom

How long did you try the PS.  It was a miracle worker on my son with the super hyper adhd, but not with my younger son with just add and not the hyper.  I have only used if for a couple days with him and so am wondering if I should continue and see if it helps after a few weeks.  Also, what dose did you use?  Sparkli have others you know noticed results right away on kids that aren't so hyper?  Thanks.

Posted: 13 April 2007 at 5:06am | IP Logged

Wow mighty mom you have made me think! My second youngest is ADD and when I tried it on him we had the same sleepy problem BUT he also was in a better mood. I was disappointed especially after the results with the youngest but I am going to give it a second try aswell.

Will let you know the results!

Thanks, inspirational. the power of sharing stories and experiences is massive

Posted: 14 April 2007 at 9:43am | IP Logged

United Kingdom breaking news!

My second youngest son (12) ADD/Aspergers! Got really grumpy and badly behaved this afternoon. Will not take tablets! Nothing will persuade him to take anything apart from Calpol (UK equiv to Tylanol). Wanting to go out this afternoon and not daring too I pierced a softgel of PS and squeezed the contents onto a piece of chocolate easter egg! 15 mins later PEACE!! I had not seen this kind of result on an ADD so I thought I would report it to the boards! The effects were not as dramatic as the 'H''s but I was still impressed. His mood just seems lighter and happier, much less oppositonal.

It has been researched and PS  is perfectly possible, safe and acceptable to mix  with chocolate! No excuses now then!!

Posted: 15 April 2007 at 2:27am | IP Logged

PS is being used and researched for Schizophrenia, Alzheimers, Rheumatoid Arthritis and Large Tumours not to mention memory in the elderly.

Seem that PS is very valuable. ADHD clinical trials are being carried out in Israel. Maybe your uncle was not schizophrenia after all, maybe he was ADHD!!! There are a lot of confusions with schizophrenia and bi-polar. I know someone who was medicated as a schizophrenic for years before finding she had been misdiagnosed.

Give PS, it is safe, natural, no side effects! You will know if it works very quickly or not. Only contraindications are if you or your son has a blood disorder or takes Warfarin. If you do DO NOT TAKE PS!

Good luck, the bigger the H the better it appears to work.

Posted: 16 April 2007 at 9:48am | IP Logged

I spent quite a bit of time researching PS this weekend. It is a phospholipid. It is the structural component of membranes. It's skeleton is linked to fatty acid molecules; it has a fatty acid tail. PS plays a "parenting" role with fatty acids. PS holds the fatty acid  in place in the cell membrane so the enzymes can metobolize the fatty acid.

PS is is involved with neurotransmitter production and packaging. PS may enhance neurotransmitter and central nervous system signal transduction. It may boost dopamine transmitter function. 

The recommended dosage is 300 mg - 500 mg daily, with the upper range being for more severe symptoms. Typical doses are 100 milligrams three time daily. It can take one month to see results!

People with antiphospholipid-antibody syndrome should avoid it. Adverse reactions: Occasional gastrointestinal side effects, such as nausea and indigestion. There are no reported drug, nutritional supplement, food or herb interactions. There are no reports of overdosage.

Several double-blind studies indicate that PS can help maintain cognitive function in older individuals and may be able to improve memory and learning skill in some. The results are not dramatic. But, given the results to date and the fact that there are so few side effects they are not dismissing PS for Alzheimers treatment.

Most of the formulas that I found also contained the phosphatidylcholine (PC) phospholipid which is curious. PC is a precursor to DMAE which has a stimulant effect. I located one product that contains only PS at organicpharmacy.org, which is also hypo-allergenic. I could not find any info on the quality of PS, but based on my experience with EPA, I suspect that quality or purity of product has some bearing.

Posted: 16 April 2007 at 11:14am | IP Logged

How strange that you say that notellin! I posted a similar thread on a different board and this is the first response I got!

This is the post below!

you would not believe it - but I have been thinking about phosphatidyl choline all day.
Can't remember when last I thought about it.

And so the thoughts kicked in - 8 or 9am UK time ... and then a thread on a sister molecule.

Weird_iss-immo mundo mundo.

Anyhow - off to read your post now - just felt the need to share the coincidence

ps ->- this is how I last drew phosphatidyl choline (it - like the other phosphatidyls - makes up the bilayer membrane of the cell).

.o
//
\\

Have recently been thinking steroid hormones too ...
not specifically today ... just recently - and a very clued up chappy with 326 IQ points PM'd me with some really really really interesting information on - what I guess is a remarkable exaptative role for, testosterone (specifically).
Must stop now - or I'll tangentickle your thread.

I think you have found something here notellin! I am going to look it up a bit more, if you find anything please do let us know. Very interesting angle! Thank you

:-)

Posted: 16 April 2007 at 11:43am | IP Logged

I just ran across something of interest.

PS was originally from cow brains, but no more due to safety issues. Now it's from soy. The problem is that the studies with PS have used cow brains as the source. It's not clear that we can assume that soy-derived PS would have the same results. Each PS molecule contains two fatty acids. The fatty acids in PS soy-derived are mostly palmitic, oleic, linoleic, and linolenic acids. These are small-chain fatty acids. PS from bovine brains have longer chains, such as DHA and arachidonic acids. The outcome of the clinical trial in Israel will be interesting.