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Alternative & Complementary Medicine
 ADHD Message Boards : Alternative & Complementary Medicine
Subject Topic: PHOSPATIDYL SERINE lifeline! Post ReplyPost New Topic
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NoTellin
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Posted: 17 April 2007 at 9:42am | IP Logged Quote NoTellin

sparkijelibean -- I used your quote as starting point for more research into this. Here's what I found.

Enzymotec is saying that their new product (SharpPS-GOLD) which combines PS and DHA uses the long-chain fatty acid. This must be the product they are using in the Isreal clinical trial? Enzymotic is an Israel R&D company. Their website says:

"SharpPSGOLD is an exclusive conjugated Phosphatidylserine-omega3 compound, which resembles to the naturally occuring (brain) PS and to the compound on which most of clinical studies were based.  Clinical research have shown It can increase omega3's bioavailability to the brain and act synergistically with DHA for an improved cognitive performance."

"An exclusive phosphatidilserine-Omega-3 conjugated compound enriched with LC-PUFA (Long Chain Poly Unsaturated Fatty Acids) for dietary supplements."

"SharpPS™ GOLD emulates human brain PS and the actual compound on which most of clinical studies were made."

"SharpPS" is just soy PS, and "SharpPS Gold" is the PS-DHA conjugate. Enzymotec says that the compound (they way they are combining it is proprietary; you can't pattern naturally occurring products, so they must be modifying it somehow). This company claims a stong effect on ADHD with the latter product. This claim is based on their studies. You can find this on the npicenter.com website if you are interested.

The argument is that DHA fish oil alone is not effective enough due to  the extent to which it can be used by the body.

Enzymotec created some type of partnership with Life Extension in the US (Florida). Life Extension reformulated their Cognitex product to include SharpPS-Gold. You can find this product on the lef.org website. It's really expensive. What's interesting is that it contains Alpha-Glyceryl Phosphoryl Choline. About 40% of alpha-GPC is choline. Choline is a nutrient the FDA now wants in all infant formula made with milk. Choline is an essential nutrient usually grouped with B complex. It is part of the cell membrane and is a chemical building block for neurotransmission.

There is also some product called Re-mind by Fischer Pharmeceuticals that uses Enymotec's OmegaPS prodiuct, but I don't think it's released in the US.



Edited by NoTellin on 17 April 2007 at 10:00am
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teric506
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Posted: 18 April 2007 at 5:56am | IP Logged Quote teric506

Good Morning All,

I actually saw a difference with Gregory last night after I gave him the PS. He was very bouncy when we got home and I gave him his PS and with 1/2 an hour he was actually sitting on the couch with me very calmly. Usually if he is on the couch he is crawling and jumping everywere. I couldnt believe it. I also got the omega stuff I ordered which was quicker than I thought it would be.  This morning was a little different though, I gave it to him when he got up because he is usually off the wall first thing in the morning and it did not seem to help like it did last night. I am not sure if it is because he was much more H than last night but I will give it some more time. I started keeping a log so after about a month I will see what happens.

Teri

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sparklijelibean
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Posted: 18 April 2007 at 6:31am | IP Logged Quote sparklijelibean

Sorry should have made one of my statements a bit clearer.

Serine and PS is available within the drug market. It is already being used as a catalyst. Check out drugs like.

Gabapentin

 Cycloserine

 there are a lot more and I can post those aswell BUT it is out there folks just not PS on its own! Very clever of the drug companies especially as we now know that the patent is owned as are the worldwide rights. I think I have posted the article in one of my previous posts on this thread.

Sorry thought I ought to clarify!

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teric506
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Posted: 19 April 2007 at 7:42am | IP Logged Quote teric506

Good Morning,

Last night was still pretty good with the PS, I gave it with the omega-3 (since they work together) about an hour before his regular meds. He was not as calm as the other night but still much calmer than normal. This morning I only gave him the PS and omegas (again and hour before his normal meds) and not the DMAE or Cal-Mag. He was calmer than yesterday morning so I am hopeful.

6kids -I saw that you only use PS, omegas, vitamins and minerals. Do you think you can let me know what you are using and what you have noticed from it. If you are not allowed to post it here can you please PM me. I am interested to know what it working for the hyperness ect. for your child.

sparklijelibean - I am very hopeful so far, I am so glad I found your post or I would have never found out about PS.  I am glad you shared your story with us.

Teri

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NoTellin
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Posted: 19 April 2007 at 11:52am | IP Logged Quote NoTellin

I am using PS, omega-3, calc-mag, antioxident, co-enzyme Q10, melatonin, a homeopathic remedy, and I've been starring at a bottle of B6 for a week now. Only the PS is new.  Since giving the PS I've gotten kudos from the math teacher. I'm hesistant to say this is the PS or that I see any significant difference since I've added the PS, but I will keep you posted. We started 9 days ago, 400 mg a day since my son's ADHD in the school environment is described as "severe." I must say it is getting rather comical giving my son basically a handful of pills each morning and night. But he dutifully swallows them all!

I still have my doubts since the clinical studies are based on the bovine-sourced PS with the long chain fatty acid tail, and I am giving him the soy-based PS with the short chain fatty acid tail. But PS appears to be totally harmless, so no harm regardless (oh, except my pocketbook -- what pricey little pills!!).

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NoTellin
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Posted: 19 April 2007 at 12:30pm | IP Logged Quote NoTellin

I'm afraid to stop the homeopathy and the omega-3. I have done that with disastrous results. I am fairly sure that the calc-mag is having a calming effect, but I would have to take it out of the picture to be sure. The only things that I'd be willing to drop are the antioxident and co-enzyme at this point. Or maybe I could give the PS alone, and continue to give the other things at a different time of day. My doubts about the PS and confidence in the omega-3 and homeopathic remedy make it very difficult to change my approach.
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sparklijelibean
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Posted: 19 April 2007 at 4:17pm | IP Logged Quote sparklijelibean

Notellin! Pleeeeeeeze just try the PS on its own just once! If there is going to be a big effect I promise you will see it quickly, maybe just give it an hour before the rest?? You can shoot me down in flames if it does not work! It is safe I promise! Honest!

Please do let us know! I had to brave it and I am a terrible one for routines! If you asked me to add anything I would be the same as you! Talk about pot and kettle!

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teric506
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Posted: 20 April 2007 at 5:42am | IP Logged Quote teric506

Good Morning,

Well I stopped giving Gregory all of his supplements except the PS and omegas and it was not a very good thing. I only gave him the PS and omegas yesterday morning and he was very hyper still (not like normal but still very hyper), school said he was very impulsive and couldnt sit still and the babysitter said he was really hyper also. When I got him home last night about 5:30 I gave him the PS and omegas, it seemed to help a little but it was hard to tell because I sent him outside to play with his brother. There was no fighting though so that was a good thing. Then I gave him his normal meds at 7. This morning I only gave him the PS and omegas about an hour before his other meds but no other supplements and he was pretty much off the wall like he normally is, jumping all over the couch, throwing himself on the floor and not listening to a word I say. 

I know it has only been a couple of days and the omegas take long time to work, but I was really hoping the PS would do more. Sometimes it seems like it works (like in the evening) and others times it does not seem to help. I give it to him 3x a day, In the morning about 6:30, then the sitter gives it to him at 2:30 (unless 1/2 day then noon) and I give it to him again at 5:30pm.

What should I do? Should I start giving him the other supplements along with the PS, or should I try something different? Any advice would be great, we are running out of options and it is very frusterating.

Teri.

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BL Moretti
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Posted: 20 April 2007 at 6:12am | IP Logged Quote BL Moretti

Teri:
My plan was to try the ps when school ends.  I am adding it into other suppliments in the AM and PM but I will try it alone when there is no longer the pressure of school.

The thing is that ADHD is really just a list of symptoms and there are hundreds of things that can cause the symptoms.  PS deficiency would be just one of those things.  Jelibean seems to have stumbled on the "thing" for her family.  It may the one for you too but there may be another thing as well.  I think the PS was helpful for my son and I intend to give it a real try, but not when he has a research paper and social studies test coming up.
What meds is your son taking?


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teric506
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Posted: 20 April 2007 at 6:22am | IP Logged Quote teric506

BL Moretti,

He is on a list of meds, he is actually autistic with extreme hyperactivity. He is on Concerta, tenex, trileptal, paxil, and risperdol. He is on a ton of medication and it helps because the results are disaterous every time we try to wean him off of something. They do help to an extent but I do not beleive they work as they should or we would not be struggling as we are. My goal is to find a supplement or a mix of supplements so I can get him off of these meds. So far I am not having very good luck.

Gregory is a very sweet and lovable kid but he has serious issues. He is so impulsive and hyperactive that it affects his and others saftey. He has major mood swings, he feels no pain, has no saftey awareness and wanders.  There has to be something I can do for him besides the therapy he already received.

 

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