Brain scans | ADHD Information
Dr. Daniel Amen and SPECT
The
activities of Dr. Daniel Amen have raised the suspicions of some
people, and - as usual - Dr. Harriet Hall has responded with some
excellent comments. Her response comes after these introductory links
and comments:
His websites
http://www.amenclinic.com/ac/default.asp
http://www.brainplace.com/bp/default.asp
His SPECT brain imaging
http://www.brainplace.com/ac/whyspect.asp
The
American Psychiatric Association and the American Academy of Pediatrics
recommend that clinical use of neuroimaging for psychiatric conditions
be delayed until studies yield evidence in support of practical
clinical applications.
APA: Practice Guideline for the Psychiatric Evaluation of Adults
AAP: Clinical practice guideline: diagnosis and evaluation of the child with attention-deficit/hyperactivity disorder.
_______________________________________________
Response by Dr. Harriet Hall, MD:
I
had not previously heard of Dr. Amen, but I have just finished
reviewing the websites, the video, and PubMed, and I am NOT impressed.
SPECT is an experimental procedure that may eventually teach us a great
deal about how the brain functions in health and disease, but it is
premature to use it for diagnosis and for guidance of treatment. In my
opinion, Dr. Amen's claims are unfounded and his approach unethical.
SPECT is an invasive procedure requiring injection of a radioactive
material, with additional radiation exposure from the scanner. The
findings have not been validated as useful in diagnosis, and as far as
I can see, all he is accomplishing is using a "picture" to help
re-inforce what we already know - that the brain is the organ that
determines behavior and psychology. He claims to be able to direct
therapy based on scan results, and there is no research to support that
claim, only anecdotal evidence and testimonials. It is unconscionable
to charge patients thousands of dollars for an unproven technique and
to give them the impression that it can accomplish more than it really
can.
Unanswered questions: do patients treated in his clinic do
better than patients treated by a competent not-SPECT-using clinic? Are
the SPECT findings consistent enough that blinded observers could agree
on the diagnosis from the scan alone? Have different treatments
actually been compared as to their effect on the scans? Is it possible
that Dr. Amen's judgment has been affected by common psychological
pitfalls such as confirmation bias? Why did he leap into clinical
applications, writing for the public, appearing on TV and the lecture
circuit with information that the rest of the medical profession
considers preliminary? Why has he not published his findings in a
reputable, peer-reviewed journal? (A pubmed search for "Amen" and
"SPECT" brought up only 7 items, all of which would be classified as
preliminary studies and none of which supplies adequate evidence to
support using SPECT scans as he is doing in his clinic.)
I
noticed two other things on his website that I found very worrisome:
the reference to "soul" (a metaphysical rather than a scientific
concept) and the use of EMDR as a therapeutic technique.
For a critique of EMDR, see:
http://www.quackwatch.org/01QuackeryRelatedTopics/emdr.html.
I would not personally submit to a SPECT scan in Dr. Amen's clinic even if it were free. In my opinion, with the present state of knowledge, the potential harm outweighs any potential benefit.
Pictures
of "your brain on drugs" may impress some people, but I am far more
impressed by specific psychometric test results and clinical
consequences than by nonspecific pictures of "holes" in the brain.
Harriet Hall, M.D.
This is your brain on booze
Alcohol's Effect on the Brain
Brain Area
Order of Development
Function
Behavior Under the Influence of Alcohol
A
5th Developed
reason, logic, intellect, judgement
may be pleasant, sociable, relaxed or excited, decreased inhibitions, impulsive behavior, talkativeness, reason and caution impaired, driving ability impaired
B,C
4th Developed
Fine Motor Skills--more difficult to master...talking, writing, tying shoes, etc.
slight decrease in fine motor skills, poor judgement, slightly slurred speech, slow reaction time, impaired hearing
D
3rd Developed
Gross Motor Skills--basic movement
confusion, staggering, unable to stand upright, slurred speech, blurred vision, impaired judgement of distance
E
2nd Developed
Semi-Voluntary--muscle coordination and balance...reflexes, such as blinking eyes, which take place on their own but can be controlled at times
muscle coordination and balance impaired, severe confusion, semi-stuporous
F
1st Developed
Vital Functions--respiration, digestion...these functions occur automatically, they keep us alive
unconscious, coma, respiratory and cardiac distress, death
Alcohol affects the brain in the reverse order of how it develops. The first area impacted by alcohol is the last to develop. Therefore, your ability to determine how drunk you are is the first area affected.
As someone drinks, you can sometimes watch them move through the various stages of intoxication. Often between the semi-voluntary and vital functions stages a person will pass out. This acts as a built-in safety restraint, preventing someone from continuing to drink more.
However, if someone drinks too much too fast, it can result in alcohol poisoning or overdose
Hey GarPaiKi,
Your Inbox is full. Ping Repairman.
Davidornado
Trust All is Well With Your Soul