SO ARE THEY SUPPORT STRATTERA OR NOT? I READ THE WHOLE THING BUT I TEND TO GLOSS OVER THINGS AND MY MIND WONDERS, (CAN'T IMAGINE WHY THOUGH, LOL) BUT I TRY TO GET THE JEST OF THINGS...IF I "GLOSSED" IT CORRECTLY IT SOUNDED LIKE STRATTERA WAS A GOOD THING AND IT MAKE ME WANT TO TRY IT AGAIN AND SEE IF I CAN GET PAST THAT ONE SIDE EFFECT OF FEELING HOSTILE AND ANGRY AT EVERYBODY AND MOODY.
A PSYCH DR. I TALKED TO BRIEFLY ON THE PHONE WHEN I TOLD HIM ABOUT THE MOOD THINGY HE SAID THAT I HAVE ADD WITH A MOOD COMPONENT. WHO KNOWS THEN SINCEI DONT HAVE A "MOOD COMPONENT" OTHERWISE THAT I KNOW OF CEPT WHEN I REALLY LET THINGS BUILD UP I MIGHT UNLEASH IN AN UNHEALTHY WAY AND BREAK A COMPUTER OR TWO, OR PUT A HOLE IN A WALL, OR SOMETHING OF THAT NATURE.
I'VE LEARNED TO CONTROL THAT THOUGH SINCE IT HAS COST ME TOO MUCHMONEY TO FIX THINGS THAT I BREAK AND THANK GOD IT HAS ONLY HAPPENED WHEN EXTREMELY PISSED AT EITHER THE COMPUTER OR MY HUBBY.
I had some luck with zoloft for ADD and depression. It really helped me study better and memorize things faster. It helped me keep my mind on on the subject matter. I made an A in Organic Chemistry 2, and an A Physics 2 with a B in Sociology the semester I was taking it.
I'm the ADD type that over-focuses on things i'm interesed in, but have tremendous trouble following conversations or directions when the subject matter is dry or there is a distraction.
I also have central auditory processing disorder, which is common for ADD, where things go in one ear and out the other when I'm distracted or not interested. I don't know why they call it auditory. I have the same problem with reading.
OpenYourEyes38326.6568518519Yes, they are saying strattera is a good thing, along with any other chemical that increases Norepinephrine in the brains prefrontal cortex.
Yeah, you have to get past the side effects concerning any medication. Side effects usually diminish after a few weeks or months. Some meds produce more or less side-effects in different people. Side-effects are a huge problem in psychopharmacolgy, because a large majority of people quit 5 days before the miracle happens. It takes a few weeks for these type of drugs to start working, and a few months for them to take full effect.
The article is saying that you have several alternatives to Strattera if you have cognitive dysfunction due to ADD, which are all drugs that increase NE in the prefrontal cortex: Duloxetine, Effexor, Reboxetine, Tricyclics, Desimpramine, Milnacipran, Stimulants...
Ive been taking Reboxetine which is a potent NE reuptake inhibitor for 6 days, and the side effects are tolerable, and I have a low tolerance.
OpenYourEyes38326.9259606482hmmmm, very interesting insights on ssri's for add. i have been on only 2.5 mgs of lexapro for three days now but forgot to take it today but have been bouncing off the walls for two days now, lol.
seems i cannot sit still but my mood has been great, yet totally unproductive though constantly been on the go..i just dont get it.
tuesday i see my dr. and am going to ask her for something for the ADD. i did not like strattera at all and am not sure she would be convinced about the ADD diagnosis though i am totally armed now with documents covering every aspect of it and how it has affected my life.
i may ask her about a TCA med instead of a STIM. not sure i like the STIM idea myself but i will see what she thinks and i have a better chance asking for a non-stim vs a stim.
any thoughts on sometihng else to try? i am thinking of disimpramine.
I don't know your story, but if we are talking ADD, then I would try the Effexor or disimpramine. Disimpramine has a lot of nasty side effects.
A new drug which is supposed to have minimal side effects is Milnacipran. It elevates Norepinephrine and Serotonin equally. It's not available in the US, but you can order it legally overseas. You might ask your Dr. about trying this medication. Here's a good article...doesnt say anything for ADD, but it increases the same chemicals in the brain as Strattera, without the horrid side effects.
http://www.antiaging-systems.com/extract/milnacipran.htm
OpenYourEyes38326.7371643518the article says it is for pain though?
i did try to get on effexor and when i went there that was when i saw the pamphlet on ADD women and then she let me try the strattera.
i guess my next line is the effexor if it helps with add and it is not a stim, then iwould like to try it anyways.
i just do not feel comfy trying the stims but i guess if she offers me something then i will try it cause that would be thee fastest way to know if it is true add or not, or so i am told.
i have so many classic symptoms of adult add and have been treated in the past with ssri's to no avail so maybe i was being treated all my life with the wrong meds for the wrong thing so i desparately want to try someting, anything!
i took desipramine many years ago and i felt so good on it but it made my heart race too much but that was at 100 mgs and i had titrated up only 10 mgs a week.
so i do not know how much desipramine one needs for ADD but am willing to try anything!
maybe when that other med comes to the U.S. i can try it then!
Yeah, the article only talks about depression and pain, but the neural increase of norepinephrine and serotonin are the biochemical basis for the treatment of ADD, also.
I wouldnt worry about trying a stimulant. It's definitely worth a try. It worked wonders on me when I was 7. As an adult, I tried Adderall and it definitely worked, but when it starts to wear off my ADD symptoms got worse than they were before I took it. It lifted my mood for about an hour, and then I would crash into depression, paranoia, and bad ADD symptoms. So, I had to find something longer lasting.
You might also look into duloxetine, just FDA approved.
Article show that NE and Serotonin concentrations are increased in prefrontal cortex.
Comparison of effects of dual transporter inhibitors on monoamine transporters and extracellular levels in rats.
Koch S, Hemrick-Luecke SK, Thompson LK, Evans DC, Threlkeld PG, Nelson DL, Perry KW, Bymaster FP.
Lilly Neuroscience Research Division, Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, IN 46285, USA.
Compounds that block both serotonin (5-HT) and norepinephrine (NE) transporters have been proposed to have improved antidepressant efficacy. We compared the ability of four dual transporter inhibitors-chlorimipramine, duloxetine, milnacipran and venlafaxine-to block monoamine transporters in vitro and in vivo and increase extracellular monoamines in rat brain. Inhibition of radioligand binding to clonal human monoamine transporters in vitro and in vivo in rats was determined. Extracellular concentrations of 5-HT and NE in rat prefrontal cortex (PFC) were quantified using the microdialysis technique. All compounds blocked binding to human 5-HT and NE transporters, although chlorimipramine and venlafaxine had markedly greater affinity for 5-HT than NE transporters. In vivo, chlorimipramine and duloxetine potently blocked both transporters, milnacipran blocked both with lower potency and venlafaxine only blocked the 5-HT transporter. Chlorimipramine and duloxetine increased robustly and approximately equally monoamine extracellular concentrations. Milnacipran produced only small increases in NE, whereas venlafaxine increased 5-HT markedly at the lower doses and both monoamines at high doses. Thus, the dual transporter inhibitors blocked 5-HT and NE transporters in vitro and in vivo with varying potency. Chlorimipramine, duloxetine, and high dose venlafaxine acted as dual transporter inhibitors in rat PFC and increased extracellular concentrations of the monoamines, indicating functional dual transporter inhibition.
Here's an excellent article explaining how these drugs affect the prefrontal cortex.
http://www.psychiatrist.com/brainstorms/br6402.pdf
i have beendown the strattera road to no avail due to feelings of anger and hostility that drove me right off it before i even got to see if it would help.
so now back to square one i am going to try some lexapro at a dose of 2.5 to start then work up to 5 or maybe 10 mgs.
i desparately need to try something as i am to start a new job next week and as per my past job record i know that i will surely fail this one too..
i am 47 and so much want to hold down a fricken job even if it is only at target! so anyone have any input as to whether or not lexapro may help with ADD symptoms???
SSRI like Lex have had some effect on ADD, but clinical data shows that ADD is affected by norepinephrine. Lex will probably help if you are depressed. Maybe its just what you needed. Its worth a trial. Its the anti-depressant with the least side effects.
It hasn't helped my ADD that much but I'm taking it for dysthmic disorder (that's chronic depression). It's okay but I worry about long term effects on my stomach and stuff like that.