Has anyone tried Intuniv? (tenex) | ADHD Information

Share
My bad - I read an article and thought it had been released. I did read the press release, HorseMom, and was encouraged by the information. Thanks for the information.

In the meantime, his Dr. increased his tenex to 2mg/day. Hopefully that is all the adjustment we need right now!Is it on the market yet?  I hadn't heard this.  A few months ago, my child's dr. said that it was slated to be released in Fall '09.Mom2ADHDboy39952.3585300926There as press release yesterday about another study.  If you google - Intuniv it should be one of the first hits.   I didn't see a release date in the article. My son is on 1.5 mg of tenex and it has been tremendous for him. We are meeting with his Dr tomorrow as we think his meds need
adjusting. We are seeing an increase in impulsivity and anxiety. I am curious if anyone has used the extended release for of tenex
(intuniv) and had good results with it.

heatherr1, if you don't mind, I'd like to ask a few questions about your Intuniv experience.  What time of day is your child taking it?  Do you notice any times of day when it works more or less?  Also, how long before the next dose does it seem to wear off, if at all?

One last question.  Since your child already was taking Tenex, did Intuniv need to build up in your child's system to be effective or were the effects immediate?

I hope both of your kids continue to do well on the meds!

 

Cherylg, I know it's probably still building up in your system, but how's Intuniv going for you?  I hope it's working out.  

Mom2ADHDboy40146.8521759259It just became available this week.  My pdoc has already prescribed it 3X this week so I guess I'll make #4.  I'm getting a starter pack plus coupon for something off my first script.  I won't get it until Fri.  BTW... it's for me (44 yo) and I've never tried tenex.  I'm adding to my vyvanse.  Wish me luck.....

Today is day 4 for us on Intuniv 2mg. I have definately seen improvement on the hyper side for ds but the moody/defiant/sad/argumentative side is worse I think. Or maybe it is more prominent since hyperness has subsided. He is tired too which I expected but looks tired too(dark circles) even though he sleeps well and sometimes cat naps on weekend now. Teacher claims still issues with arguing with kids in school

I really do not want to have to give ds 2 meds at 7yo, and I woory 3mg will make him even more tired.He is 50lbs.Anyone at a higher dose and same size?

Need to call md Wed to get RX for Saturday after starter pak is up.

kevnec and heatherr1, I know it seems strange because the long acting med is supposed to be the same as the short acting one but my son couldn't take any of the long acting stims. He does very well with the short acting type but has horrible problems when he switches to the long acting.  I don't know if Tenex/Intuniv are the same but it may be that you need to go back to the Tenex.  When my child started Intuniv and for the first few days on a new dose, I've noticed increased irritability and being more emotional.  Then his body seems to adjust and this settles down.  Same goes for fatigue, I've seen it at first but then it settles down.We have been tapering off the Intuniv and will be off next Mon. My ds had similar sx's with increased irritbaility/emotions that did not go away. MD has had us taper down from the 2mg dose and we will try Strattera next.

Dear Mom2ADHDboy,

You mentioned that your son was more emotional/irritable when starting a new dose on Intuniv.  How long has he been on it now?  At what dose did you end up with?  We are day 5 of 4mg.  My son seems VERY emotional.  When he is happy it is like he is drunk, but when he is sad he cries and gets angry at himself and says he is mad at the world.  It goes back and forth throughout the day.  Am wondering if this will subside or if we need to go back down to 3mg.

Thanks in advance for any input.

 

Just started my daughter on Intuniv after 2 and a half years on Vyvanse.  She is just at the end of the 2mg dose and we start 3mg on Monday.  We have noticed a huge difference in our daughter's behavior.  She is happy, compliant and not threatening to run away or kill herself (she is 9) anymore.  She only has the inattentiveness, so hyperactivity isn't an issue we need to control.  She has not been in school with it yet, but I am keeping my fingers crossed that she will be able to focus better.  The Vyvanse worked great, but after awhile seemed to be wearing off and rather than put her on a booster dose of something the dr put her on this.  I have been giving it to her in the early evening, around 6 or 7 as I have noticed it doesn't really seem to make her sleepy until about 3-4 hours later, but we also give her a melatonin to help.  She has been waking up happy, eating really well (she went from 48 lbs to 53lbs in 1 week) and if I ask her to put something away, she will do it without complaint (it was a huge battle before...so much so, I usually ended up doing it myself because I didn't feel like arguing with her).  Hopefully this will work in school too...will let you know in a few weeks time.
I have two boys (ages 9 and 11) with severe ADHD. The 9 year old's hyperactivity is almost manic-like and the 11 year old has anxiety issues as well. They're both on 54mg concerta a day, and the 9yr old also on Tenex. The Dr. now has them trying Intuniv over the winter break. We're up to 3mg this week. The 11yr old is waking up at night around 3am and having a hard time getting back to sleep. The 9yr old is having same problem plus VERY emotional and his hyperactivity isn't much better. They both look really tired and their eyes have that "look" like they're on drugs. I hope things get better with this Intuniv soon. I think we're going to stay at the 3mg level for a little while. Maybe they need more time to adjust. Reading all the posts here has helped me, so I hoped that my post might help someone else. Willsmama, it takes 3-4 weeks to build up in the system.  How long has he been taking it?Since February, I believe.

My son's dr said it wouldn't be available until Nov 11th.

So far, tenex hasn't done a thing for Will.  His dr did up his dosage to 2mg in the am and in the morning.  Maybe that will help.

Has anyone seen this help with tics?

My daughter just received her prescription yesterday for Intuniv.  Too soon to tell if it helps but I am hopeful. We saw a reduction of tics on Tenex, but it didn't totally make them go away.  It helped make her a little more even keel and less anxious - which I think help reduce the tics. Anthony,
Are you worried about the sleepiness?  From what I can see it gets better as it goes along.  DS ended the week not feeling as sleepy.  I am hoping that my DS can be on the Intuniv alone, but I have a feeling he will still need a stimulant.  Good luck to you, I know it is so hard to figure it all out.

Right now my son is taking intuniv and metadate. The doc said we might be able to get off the metadate but we will have to see. He goes back for a 2 week check up from the sample of intuniv so he hasnt been on it long, but so far so good. He is having the sleepiness but i think between the stimulant making him not go to sleep and the intuniv causing it it has evened him out.  Also with just the stimulant he didnt want to eat alot now with both he is eating normally again.

my son is 7 and was originally on tenex ,1 mg in the
a.m.,1
mg after school then 2 mg at bedtime. he has ADD.now he
just got put
on
intuniv,2mg. i am so afraid to give it to him in the a.m.
cuz i dont want him to be tired so i started it at
night,but the problem is he was not able to fall
asleep.he
was on trazadone 50 mg and that also takes about 3 hrs.
to
put him to sleep so i am now trying melatonin.i think i
am
going to try it tomorrow morning before school. i am just
nervous as i said.any one have any input please feel free
to either send me messages or post something here..my son
also has some anxiety and is very emotional .that is one
of the reasons he is not on a stimulant and we did
straterra and it worked great but constipated him so
badly.jennipha40161.4851041667

My 10 yr old son was previously on Tenex 1mg 2x a day and decided to try Intuniv.  We are on day 5 of 2mg.  I can't say that I have noticed anything other than extreme tiredness.  He has been off an on stimulants since age 6.  Adderall XR worked well for a year or so, but then we started noticing adverse effects (aggression/anger, etc).  He also has anxiety so the mix with antidepressants probably doesn't help the with the adverse effects.

I am hoping that once we ramp up to 3 or 4mg I will see a noticeable difference.

 

We are on our second week of Intuniv. First week DD (6) took it w/ Vyvanse, but still had some severe anxiety, so for the past five days she has been on Intuniv only.

I've noticed it takes a good couple hours in the a.m. before she is calm, but perhaps this is because it has only been two weeks and it is not fully in her system yet? She has been very sleepy, but this seems to be improving - yesterday is the first day she has not taken a nap.

I think in general she is happier and more compliant on this med than on the Vyvanse, but I am worried because her attention has not improved. I am thinking we might have to add a stimulant back into the mix?

Heather...he does have a hard time falling asleep when he is on the stims,takes him a good hour or so before he finds his comfort zone(tossing and turning and he must go to the bathroom a good 4 times.

But on the tenex he fights it for 10 maybe 20 minutes before he crashes.

We have given him a break from the Adderall to see if the tics subside but i hope he can somewhat function well just on the Tenex.

I think if he can handle school without the stims we might really push for the Tenex at a higher dose.Good luck to and your lil one too Heather.    

Anthonyd40154.5147685185 Does Intuniv truly last 24 hours, or is there a period where it's clearly worn off before the next dose is due?  If there is a period where it's worn off, about how long does that last?

Also, if there's a gap, how long after taking the pill before it starts working?


Mom2ADHDboy40154.8504050926I haven't posted for a while..... I'm on my 2nd week of 3 mgs. and I believe it's really different for an adult.  I never really got that super drowsy period (except maybe the first couple of days I took it).  It has really extended my Vyvanse (70 or 80mg. depending on my day).  I've stopped needing an afternoon boost of short acting dex.  I take my dose at about 7am and I feel like I'm good until at least 7 pm.  I think I'm better even beyond that than I was on stimulants alone so the Intuniv must be helping.

The only negatives for me is I now hyper focus a little more.  I may need to lower the vyvanse maybe?  The 70mg. was not working as well for me when I added the intuniv, now it may be a little too much.  For me, I don't think the Intuniv alone would cut it.  I have moderate to severe adhd and am a fast metabolizer of the stimulants.
I can't really tell yet how long it takes to kick in, but it is still working 14hrs later at bedtime. 

My DD(14) said she feels like Intuniv makes her hyperfocus more.  She was on Vyvanse 50mg and it didn't seem like hyperfocusing was really an issue.  She is on Intuniv alone due to the Vyvanse increasing her anxiety, and has said that the hyperfocusing isn't enough of an issue to quit taking Intuniv.  She is on 4mg.


Another update...

I noticed DS having tics last night about 13 hrs after taking his med in the morning.  He was having alot of tics:( 

I have already noticed a few tics today and he just came home from school.

When Christmas break starts next week I am going to have him on just the Intuniv.  If he can handle school in January with just Intuniv we will do that.  If he still needs his patch, we will probably go back to Tenex twice a day.  It controls the tics better, I think.

Thats very interesting in the sense that Tenex and Intuniv is suppose to be the same but in a time release form.Maybe it takes a lil while to build up in her system?Give it some time to see if thats the case.

I really do not want him on any stims cause of the bad side effects that he gets(tics and moodiness)but on the bright side he did focus very well in class...a lil bit of hyperfocus in some things but we couldn't bear to see him with those horrible tics.

Good luck with your lil girl and please give the meds some time to build up to get the full observation from the Intuniv.Thats the one thing that us as parents don't really do(we get super nervous seeing our babies going thru stuff)Breaks our hearts. 

Just wanted to update since we took my son off the stims about i would say almost a month.His tics have somewhat subsided but still very much there but if i recall it took him a while after we removed him from the stims last time so i am hopeful they will this time again.

He has had good days at school and home but also really rough ones where he is really defiant and mouthy but i think thats cause he is 10 yrs old going on 18...we are working on that aspect.I definitely want to keep him off the stims and push the Dr for the intuniv on our next appt.I feel in my heart that this could be the med that helps him the most and helps him be the kid that can excel in all aspects of life.

Would like to hear from anyone who has seen progress in their own experience with this new med. 

My daughter (7yo) dx adhd with ODD tried stims but they were disastrous.  We switched to Tenex 1mg and it worked great.  Then we switched to Intuniv since it is the same thing as Tenex just extended release so we would only have to give 1X/day.  Ever since then, things have gone downhill.  We originally put her on 1mg intuniv but DR said it was not equivalent to the 1mg of Tenex so we upped it to 2mg.  She has been on 2mg for about 2 weeks and we definitely see a difference in that she seemed much better on the Tenex than the Intuniv for some reason.  We have an appt with Psychiatrist to discuss.  I don't get it. I am kind of seeing the same thing.  I think that Tenex worked better for DS than Intuniv, at least taken along with his stim.  He is on 3mg Intuniv alone over the holiday break.  It does help, but I can't imagine him in his classroom and trying to focus.  I may up him to 4mg before his starts school again, but I am reluctant because the 3mg still makes him so tired.

I was so hopeful that Intuniv would help him get off the stim, but I am not sure it will work.

On the flip side, the Intuniv has helped DD, she is on it along with Zoloft, but she is inattentive type so no hyper or impulsive issues to worry about.

Thats where i get worried that it wouldn't help him Heather...its extremely nerve wrecking trying to figure what works or what doesn't.

He has always responded well to new treatment but after 30 days or so it would go back to him having tics or really ocd'ing(washing of the hands or going to the bathroom like alot).I pray that it will help him with this because he is doing alot better socially and academically since he started the Tenex only.

Ugh...its taking a toll on everyone home and we want to stop stressing  soooo bad.

   

3 mg looks like it might be the right dose for my ds (10 years old, around 65 pounds I think), combined with Metadate CD and Zoloft.  He's taken it for only three days, so it's a bit soon to judge.  I look forward to hearing how he does at school.  He was having a lot of problems in November and December.

Once again, he was super emotional and irritable the first few days on a new dose.  It's gotten better and better over the past three days, with almost no issues today (Day 3 of 3 mg). 

Moorekiddos, 5 days seems like a long time to be seeing the heightened emotionality.  Did your child take Tenex before Intuniv?  If not, I guess it's to be expected that it could take awhile to get used to it.  What does the doctor say?  Did you see increased emotionality in the first few days at lower doses?

Hold2Hope, your children seem to be going through something similar to what my child experienced with Tenex.  We discovered that, if he took the afternoon dose later than 3:30 pm, he would be awake at around 3 am for awhile. 

With transitioning from Tenex to Intuniv, my doctor had me taper down the Tenex while adding the Intuniv.  My son did fine until we got to 2 mg Intuniv.  At that point, we did no Tenex in the morning and 1/2 mg in the afternoon (previously he'd taken 1 mg Tenex in the morning and 1.5 mg in the afternoon).  Once again, he was up at 3 am when he had 2 mg Intuniv and 1/2 mg Tenex in pm only.  When we discontinued the Tenex, he returned to sleeping fine.  He's even done fine with 3 mg Intuniv.

My DD was slowly going up in dosage on the Intuniv.  She was like a completely different child on the 1mg and 2mg (in a good way).  She started 3mg 2days ago and on 3mg.  she is having a hard time focusing in school and listening at home...is it possible she is on too high a dose?  Would that cause the off behavior when she was so good on 1 mg less?  I know it is a dumb question, but just wondering.
Wow, this Intuniv is some powerful stuff. It sounds like we're all going down different paths with it. My 9yr ds is doing well on 3mg but still somewhat hyper, might have to go to 4mg. We'll see, need to give it a bit more time. My 11yr ds totally different story...he got up to 3mg and couldn't sleep, acted a little strange, and his eyes looked wierd. I backed him off to the 2mg and he slept better but he's having hallucinations at night(3am). NEVER has he had hallucinations. I called the Dr. and we're weening him off starting tomorrow morning. He also takes Concerta, he has for years and never had anything happen like this. This freaked me out. My ds is handling it way better than I am. I'm starting to think that the Dr.'s are tritrating this stuff too fast. Maybe one week isn't enough time to tell if the dose is enough or too much. I don't know what to think.

Hold2Hope- My ds son's eyes were very bloodshot as well while on it.We are off it now for a few days and on Strattera. Intuniv made him VERY confrontational and irritable.Also super emotional and tired.He only made it to 2mg. DS is sensitive to meds I am realizing now.

 

We do know Intuniv is not for him...but mostly not for US!

rhody94, we've never experienced the Tenex (short acting Intuniv) dose being to high but we have experienced when other meds are too high and I would say YES, the dose being too high can make things worse!  For instance, we are trying Strattera right now and it was working pretty well then he all of a sudden got MORE hyper and really aggiatated.  We had been gradually increasing the dose and when the dose got too high for him he started going backwards and the side effects made it look like the ADHD symptoms were back but it was really just that the dose had gotten too high.

That's usually how the docs know what the best dose is for any particular patient.  They increase the dose until the benefits are outweighted by the negative side effects.  This shows them that the dose is too high, so they back it off just enough to get rid of the side effects and that's usually the optimal dose.

My son took his 7th 1mg dose of tenex today;  We've already seen a huge change in his behavior and frustration levels... Tomorrow we are supposed to increase to 2mg and I'm wondering what to expect.

Does the smaller dose not become enough and that's why you increase?  I'm hoping that we aren't playing with fire by changing the dose now that things are better.

rachel

I agree with the pp.  If you are not seeing any ADHD behaviors, then I'd stay at tht dose.  However, I'd be ready for him most likely to adjust it and be prepared to go up at that time.

While stimulants are not age or weght based, Intuniv is a weight-based medication.  This means you can predict based on weight what the best dose will be.  However, if you're seeing perffect ADHD control at 1 mg, I wouldn't increase.

Both of my kids are on Intuniv.  My DS 11 was on 1mg Tenex in the morning, with a 1/2 dose when he got home from school.  He is ADHD, and also on Daytrana 15mg.  I really like the Tenex.  It controlled the tics, no side effects, and seem to make him eat more.  Since he was already on Tenex, doc said we could start with 2mg Intuniv.  Problem is every time he takes the 2mg Intuniv with the patch he has a horrible headache.  We tried 2mg without the patch and he had a headache plus no focus, not a good couple of days.  So, he is on 1mg with the patch, and we are planning on titrating him up over Christmas break.  It does seem to keep him on an even keel, but I am noticing a few tics and appetite is down.  He does take a 2mg pill on the weekends without the patch and works great for behaviors and attitude, which does not happen with the Tenex alone.

My DD 14 is ADD and OCD.  We are trying Tenex because the stimulants cause her anxiety to increase, thus her OCD was a big problem.  She is titrating up and started 3mg today.  She is doing great.  I am not noticing any side effects, and she is much happier. 

Heather


I'm not an expert but I can tell you my son's experience.  Whenever we start a new medication we see at least some results right away (even recently with Strattera).  Then usually after a day or two his body adjusts to the medication and starts to go back to the way it was before.  That's when the doc increases the dose.  Then the cycle starts over again.  As long as we see better results with each increase we continue to increase it until the negative side effects appear. 

Usually with my son, the dose is increased because the smaller dose isn't doing the trick and that's obvious from the start or at least after a few days.  Even if things have gotten a lot better, there are still ADHD symptoms showing through.  That's why we increase.  If your son's behavior is as good as you want it and he's stayed that way for a little while then I don't know that you need to increase the dosage.

Well, Intuniv was a big bust for us. We had to take my 11yr ds off due to hallucinations at night. The Dr. called Shire and reported it because he hadn't heard of that side effect. Shire said yes-but it was very rare. My 9yr ds started hearing things at night. He would wake up and come running into my room with his fingers in his ears at least 2 times every night. This started when he went to the 3mg, the 2mg wasn't enough to control his hyperactivity. So now they're both back on regular Tenex and doing okay. I'm gald to hear that some of you are doing well on Intuniv. Never stop trying, right?? :)We have been trying different things with the time of day the kids take the meds.  We started off taking it in the morning, but when both kids titrated up to 3mg they were getting sleepy during the day.  DS tried it at night a few times, but says that he has trouble going to sleep when he takes it at night.  I noticed that when it takes it at night, around 10 or so during the break, about 17 hours later he was knocked out.  DS started 4mg yesterday, and asked to take it in the morning again.  He did fine today, said he was a little bit sleepy, but not much.  Right now he is also taking it with Daytrana, but our hope is to get him adjusted to 3 or 4, then take away the patch over Christmas break.  I think the Intuniv does need to build up a little in the system, we are definitely seeing better results on the higher dosages.  He is much "level" than with the Tenex.

DD is doing great on Intuniv, she is up to 4mg.  We will see after these next few days whether to fill the scripts for 3 or 4mgs.  She decided to try it at night last night, and is at a friends house so I haven't gotten her report yet. 

Keeping our fingers crossed that this keeps working!
Just a little update.  I talked to DD last night, and she said that she wants to stay on 4mgs.  She said it really helps her focus, but she also finds herself hyperfocusing more.  But, she said more good than bad.  She has decided to keep taking it at night.

DS told me this morning that 4mg is too much, it makes him too sleepy.  Our plan is to get a script for 3mg and try that for a month and see how it goes.  I read that Intuniv may be prescribed off label for ODD.  If that is the case I definitely want DS to keep on it. Because although he has never been diagnosed, he seems to have those tendencies. 


My dd is on her fourth day of Intuiv. She takes it along w/ 20 mg of Vyvanse in the a.m. We are noticing more even emotions already, but it doesn't seem to have impacted her OCD tendencies - at least not yet.

My worry: She seems very tired and sluggish, but then again she had a tired period in the middle of the day when she was on Vyvanse only. I am thinking the combo makes her "double tired" - but maybe it doesn't work that way?

I am thinking of asking the pediatric neuro if we can drop the Vyvanse and just do the Intuiv and see how that goes. Is anyone on Intuiv only?

yes, my daughter is on intuniv alone (1mg) and it has helped her tremendously.  She was on 1mg tenex and this is even better.  She has MAJOR mood issues along with the add and it helps her mood and anger tremendously with no side effects.  Sometimes I think "less is more"  Less meds and smaller dose.  Most people (parents and drs) seem to increase meds that aren't getting the desired effect but I have found keeping the dose low and the right med given alone has been the best bet for my daughter. My DD is on Intuniv along with Zoloft.  She has seriously battled OCD for the past year and a half.  Her symptoms are MUCH better on the Intuniv.  The Vyvanse really increased her anxiety and the OCD.  Once she started Intuniv we dropped her Zoloft dose also.  She is a skin picker, and it is obvious that she is doing alot better.   My DD has ADD inattentive type, and so far the Intuniv really seems to work for her. 
My son is on Metadate CR and has developed a tic where he turns his head to the side. We went to the doctor today and they prescribed him intuniv to try with the metadate. So we will start tomorrow with that so hopefully it goes good. And good luck to the rest of you too.My son is taking the Adderall 15 mg and Tenex and Efexor and he is not doing so well(really bad tics) ...my wife was at the dr's on monday and asked about Intuniv for him and he said he is on tenex which is the same thing.I wanna do research on this cause its sounds like it could work well for him since the stimulants have an adverse effect on him. Another little update....

DS is holding steady at 3mgs.  His sleepiness is decreasing, and his teacher said that he had a great week this week at school.  Barely any mumbling and blurting out, which is a major improvement for him.

Tenex and Intuniv are the same med, except that Intuniv is extended release.  What I noticed between the two is that when DS was on Tenex he would take 1mg in the morning, and need 1/2mg when he came home from school to keep him steady.  He is much more even on the extended release Intuniv.

I will be picking up DD and DS's first full prescriptions from the pharmacy soon, and I can't believe how expensive it is compared to generic guaficine.  It was about for a month of guaficine, but almost for Intuniv!  Oh well, what can you expect with a new drug.

I have a gut feeling that he needs to be off the stimulants and i for one am leaning towards Intuniv but i am so disheartened about the side effects that its hard to be optimistic.

We are definitely going to inquire more info on it from his neuro next appt which is in two weeks.

I wish you all the luck in the world that it works for your children and for my boy also if we put him on that one. 

[QUOTE=zacnautysmommy]My son is on Metadate CR and has developed a tic where he turns his head to the side. We went to the doctor today and they prescribed him intuniv to try with the metadate. So we will start tomorrow with that so hopefully it goes good. And good luck to the rest of you too.[/QUOTE]

Hi! Our son just had his appointment with the ADHD Psychiatrist at CHOP yesterday and she noticed some tics too! He is also (was also) on Metadate CD 30mgs.... and today was his first day of 1mg Intuniv... but alone.... How are you making out with the Intuniv and how long til you saw a response?

thank you so much!
[QUOTE=Mom2ADHDboy]

I agree with the pp.  If you are not seeing any ADHD behaviors, then I'd stay at tht dose.  However, I'd be ready for him most likely to adjust it and be prepared to go up at that time.

While stimulants are not age or weght based, Intuniv is a weight-based medication.  This means you can predict based on weight what the best dose will be.  However, if you're seeing perffect ADHD control at 1 mg, I wouldn't increase.

[/QUOTE]


how long after you started the 1mg did you see the adhd symptoms decrease? thanks!