Hi My name is Roxan, I had a few questions, if anyone can help. I have two sons with Asperger Syndrome. The ped. suggested that they go off all meds for the summer. I AM GOING NUTS!!! Those of you not familiar with AS, it's similar in appearance to ADHD, only it's actually a form of Autisim. I have started taking ST. John's wort two days ago, to help me to cope with them. yesterday I noticed no change, today though, I am feeling extremely tired, and sort of irritable ( more than ususal). after only using the St. John's Wort for two days, I'm wondering if this is a side effect, already? Of if It still has to get into my system for a while before I can make that call? I am also wondering if anyone knows what I can do for the fatigue I am experienceing if it IS the St. John's Wort? I know that I need some help to try to "chill out" so I don't want to stop taking it unless I HAVE to. Also, if anyone knows, how long before this stuff starts to work? weeks? days? Can anyone help???? Please? Thanks, Roxan